3 days ago · The most profitable company in the US is Microsoft (MSFT) with a net income of $125.216B over the past 12 months, followed by Apple (AAPL) and NVIDIA (NVDA). Last updated May 13, 2026. Ranking of the most profitable companies by net income from 2009-2026. See which US companies made the most profit including Apple, Microsoft, Berkshire Hathaway. Ranked list of the 100 US stocks with the highest net income in FY 2026. See the 500 largest US companies ranked by revenue. This is the list of the world's most profitable public companies by earnings (TTM). Oct 23, 2025 · This list rounds up the top performing publicly listed companies in the U.S., characterized by revenue growth as well as financial security. Feb 21, 2026 · Complete list of Fortune 500 companies for 2026 with rank, revenue, CEO, industry, employees, and headquarters. Search, sort, and explore the full Fortune 500 list.